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Self-Distillative Exemplar Replay for Incremental Drug Identification

A deep-learning-driven recognition pipeline for medication safety, designed to retain prior visual knowledge while learning newly added drug classes.

Continual Learning Deep Learning Healthcare AI

Status

PAPER_ACCEPTED_ICMHI_2026
PROJECT_FACTS
Domain Deep Learning
Type Research
Role Author
Duration 2025 - 2026
EXTERNAL_LINKS
Paper PDF Slide

01. OVERVIEW

This project addresses catastrophic forgetting in incremental drug identification. The proposed framework enables models to absorb new medication classes without sacrificing performance on previously learned ones.

By integrating self-distillation with exemplar replay, the system preserves representative memory samples and distills historical decision boundaries, ensuring high-fidelity recognition in dynamic clinical environments.

02. PROBLEM_AND_APPROACH

Problem

Catastrophic Forgetting

Traditional fine-tuning on new medication categories causes a rapid decline in recognition accuracy for previously learned classes.

Approach

Self-Distillative Exemplar Replay

The framework preserves a fixed budget of representative memory samples while using soft-target supervision to distill historical decision boundaries into the updated model.

03. KEY_RESULTS

99%+

Average Recognition Accuracy

-1.75%

Forgetting

04. PROJECT_CAROUSEL

05. EXPERIMENT_TABLE

TABLE_A / Top-1 Accuracy across Training Methods

Training Method Initial Task (Task1) Final Task(Task9) Average Accuracy
Fine-Tuning 100.00% 10.89% 20.79%
Conventional 100.00% 99.20% 99.20%
Distillation-based Replay 100.00% 99.11% 99.72%

TABLE_B / Comparison of Continual Learning Metrics Across Training Methods

Training Method Forgetting Measure Forward Transfer Backward Transfer Note
Conventional 0.0375 0.94375 -0.0375 FT Baseline = 1/20 = 0.05
Distillation-based Replay 0.0175 0.95 -0.0175 Best overall balance

06. PERFORMANCE_CHARTS

Training Time across Incremental Tasks

TECH_STACK
Python PyTorch OpenCV YOLO